Northern Michigan's News LeaderHealthy Living: Off Label Drugs

Healthy Living: Off Label Drugs

Posted: Updated:

Meant for a specific condition, but prescribed to treat another. It's called off-label drug use...and doctors around the country are doing it for their patients.  Robyn Haines tells us some benefits and potential dangers in today's Healthy Living.

 

International opera star Marquita Lister was diagnosed with Polymyositis. It attacks the lungs and muscles.  A medical team at national rehabilitation hospital came up with an innovative form of therapy, including a drug normally used to treat lymphoma patients.

 

Doctors took a chance with the off-label drug use... and it paid off. Marquita pulled through. Experts say as many as one in five prescriptions in the u-s is used for something it's not approved for by the FDA. And it's perfectly legal. 

 

Antipsychotic drugs are often prescribed for dementia-- anxiety drugs are used as sleep aids... And some cancer drugs for eye problems. Off-label drugs worked for Marquita, but they aren't safe in all cases. Studies show some anti-psychotics used to treat elderly patients with dementia did show benefits, but also increased risk of death.

 

Other studies found a drug used to help patients from bleeding uncontrollably during surgery, increased the odds of blood clots, when used off-label. There is a legal battle brewing right now between manufacturers and the FDA over the off-label rule. Manufacturers claim it violates their first amendment rights.